SI�ANLARDA PEN�S�L�N G �LE OLU�TURULAN EP�LEPT�K N�BETLER �ZER�NE N�MOD�P�N'�N ETK�S�

ISSN 1300-7157

Anasayfa | �leti�im

Cilt : 26 Say� : 3 Y�l: 2020

SI�ANLARDA PEN�S�L�N G �LE OLU�TURULAN EP�LEPT�K N�BETLER �ZER�NE N�MOD�P�N'�N ETK�S� [Epilepsi]

Epilepsi. 1995; 1(3): 133-136

SI�ANLARDA PEN�S�L�N G �LE OLU�TURULAN EP�LEPT�K N�BETLER �ZER�NE N�MOD�P�N'�N ETK�S�

� Faruk TURAN¹, Mustafa BAKAR¹, �brahim BORA¹, Suat �EL�K¹, Mehmet ZAR�FO�LU¹, Sad�k SADIKO�LU¹, Erhan O�UL¹
Uluda� �niversitesi T�p Fak�ltesi N�roloji AD

Bu �al��mada s��anlarda Penisilin G ile olu�turulmu� epilepsi n�betleri �zerine farkl� dozlarda (0.5, 1, 2 mg/kg) Nimodipin'in etkisi ara�t�r�ld�. Nimodipin'in artan dozlar�n�n tek uygulamas�ndan sonra, plaseboya oranla epilepsi n�betlerinin anlaml� olarak azald�� g�r�ld�.

Anahtar Kelimeler: PEN�S�L�N G, DENEYSEL EP�LEPS�, N�MOD�P�NE

EFFECTS OF NIMODIPINE ON PENICILLIN-INDUCED EPILEPTIC SEIZURES IN RATS

� Faruk TURAN¹, Mustafa BAKAR¹, �brahim BORA¹, Suat �EL�K¹, Mehmet ZAR�FO�LU¹, Sad�k SADIKO�LU¹, Erhan O�UL¹
Uluda� �niversitesi T�p Fak�ltesi N�roloji AD

In this study, we investigated the effect of different doses of nimodipine on Penicillin G induced epileptic seizures in rats. Single doses of nimodipine administered for prophylaxis was observed to reduce seizure activity statistically significant than plasebo.

Keywords: PENICILLIN G, EXPERIMENTAL EPILEPSY, NIMODIPINE

� Faruk TURAN, Mustafa BAKAR, �brahim BORA, Suat �EL�K, Mehmet ZAR�FO�LU, Sad�k SADIKO�LU, Erhan O�UL. EFFECTS OF NIMODIPINE ON PENICILLIN-INDUCED EPILEPTIC SEIZURES IN RATS. Epilepsi. 1995; 1(3): 133-136

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